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Is There Any Over the Counter Medicine for High Blood Is There Any Over the Counter Medicine for High Blood Blood Pressure UK High blood pressure (hypertension) - NHS Chronic high blood pressure increases your risk for heart disease and, over time, can compromise the ability of blood to reach the brain, kidneys, eyes, and heart. Blood pressure readings have two numbers. The top one is your systolic number (the pressure in your blood vessels when your heart contracts). Diastolic blood pressure is the force of blood against your artery walls when the heart relaxes in between the beats and is filled with blood by the coronary artery and gets oxygen.